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Free Shipping on Orders over ¥9,900 within Japan and over ¥35,000 (Approx. US$230) internationally 

Sleek white bottle with a gold label and a cap in a white background
Exosome Messenger Serum is an innovative Japanese skincare solution carefully formulated with premium active ingredients. At its core lies the incredible power of Stem Cell Exosomes and Growth Factors, featuring a potent combination of adipose-tissue stem cell-derived exosomes, umbilical cord-derived exosomes, and dental pulp stem cell growth factors.
This triple dose of regenerative components works synergistically to optimize your skin's natural renewal process.
 
In addition, the serum also contains cutting-edge ingredients, such as Nicotinamide Adenine Dinucleotide, PDRN, and Bakuchiol, among others. These powerful additions further support a healthy, vibrant glow, working in tandem to supercharge your skin's natural rejuvenation process.
 
Made in Japan

Exosome Messenger Serum (40ml) | Japanese Skincare

¥15,180Price
Quantity

  • Introducing a professional-grade serum powered by stem cell exosomes and growth factors, meticulously formulated with high-performance active ingredients.


    Exosome Messenger Serum contains a triple blend of stem cell culture medium and exosomes, in addition to carefully selected active ingredients, including Bakuchiol (a plant-based retinol alternative that does not cause retinoid reactions) and Nicotinamide Adenine Dinucleotide (NAD+, a coenzyme responsible for supplying energy for the cells).

     

    What Are Exosomes?

    Exosomes are tiny vesicles (capsules) that stem cells naturally secrete. They serve as a cellular messaging system, delivering vital components like growth factors, proteins, and nucleic acids to other cells. In the context of skincare, exosomes are increasingly recognized for their potential to promote skin health and regeneration. When topically applied, these exosomes can transfer their contents and triggering cellular processes that stimulate collagen production, enhance skin barrier function, and promote overall skin rejuvenation.

     

    Where Are These Exosomes Sourced From?

    At a state-of-the-art facility, a team of dedicated lab scientists and technicians conduct research and cultivate stem cells in Japan. Maintaining a highly advanced cleanroom environment, they prioritize the highest quality standards throughout the whole process at their in-house lab facility. 

    🤓 To learn more about how exosomes and growth factors work, check out this article!

     

    Exosome Messenger Serum features a unique blend of 3 powerful stem cell-derived ingredients:

    • Human Adipose Derived Mesenchymal Cell Exosomes, derived from fat stem cells, is renowned for their high concentration of FGF. This growth factor is known to effectively stimulate collagen production, enhancing your skin's youthful appearance. 

    • Human Umbilical Mesenchymal Stem Cell Exosomes, derived from the umbilical cord, are known to contain a potent and concentrated blend of youthful stem cell components, delivering a richer supply of fresh growth factors to support skin rejuvenation and regeneration.

    • Human Dental Pulp Stem Cell Conditioned Media, which contains over 70 varieties of growth factors. Notably high in EGF, this medium aids in regulating skin cell turnover and promoting epidermal regeneration, leaving your skin looking healthy and radiant.

     

    In addition to the regenerative power of a triple dose of exosomes and growth factors, this serum features carefully selected supporting ingredients—each potent enough to be considered a main ingredient in its own right.

    • Hydrolyzed Sodium DNA (also known as PDRN), a DNA fragment derived from salmon, known for its remarkable similarity to human DNA. It offers powerful repairing and anti-inflammatory benefits, promoting skin regeneration and recovery.
    • Nicotinamide Adenine Dinucleotide (NAD+), Nicotinamide Mononucleotide (NMN) work at a cellular level to revitalize skin by supplying essential energy to skin cells.
    • Bakuchiol is a plant-based alternative to retinol that helps normalize skin cell turnover and stimulate collagen production—without the irritation commonly associated with retinoids. Gentle yet effective, it’s also safe for use during pregnancy.
    • Dipeptide Diaminobutyroyl Benzylamide Diacetate (also known as Syn-Ake) is a synthetic peptide that targets fine lines and wrinkles caused by facial expressions. It mimics the effect of Botox by helping to relax facial muscles, resulting in a smoother appreance.
    • Palmitoyl Dipeptide-5, Diaminobutyroyl Hydroxythreonine, Micrococcus Lysate to help repair and protect the skin.
    • Bifida Ferment Lysate, Enterococcus Faecalis/Placenta Ferment Filtrate, Alteromonas Ferment Extract - These fermented components help maintain healthy microbiome on the skin
    • Ceramides, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Succinoyl Atelocollagen, Soluble Collagen, Squalane, Alteromonas Ferment Extract and various types of Peptides to deepy hydrate and retain moisture.

     

    This serum is more than just an exosome treatment—it's the ultimate regenerative, hydrating, and protective formula, designed to address a wide range of skin concerns with powerful, science-backed ingredients.

     

  • Where are you located?
    My Tokyo salon is located in the trendy Jingumae neighborhood, near the popular districts of Omotesando, Harajuku and Shibuya districts. The full address will be provided at the time of booking, as my salon is a private space, located on the 4th floor of a charming vintage walk-up building. Area Address: 5-12 Jingumae, Shibuya-ku, Tokyo 150-0001
  • How do I make an appointment?
    To make an appointment, you can submit a booking inquiry on my website or simply DM me on my Instagram @glow.by.tomoko I am usually in my treatment room during the day, so I may not be able to answer your phone calls. Please submit a booking inquiry via my website, email or DM.
  • What's your cancelation policy?
    I want to kindly emphasize the importance of letting me know as soon as possible if you need to reschedule or cancel your appointment. This will not only help my small business but also allow me to notify clients who may be waiting for an appointment slot. If you know that you will not be able to make your appointment, please let me know as soon as possible (preferably 48 hours in advance, but 24 hours at the latest) so that I can update my schedule and make adjustments if necessary. I always try to accommodate my clients' needs and appreciate your understanding and cooperation.
  • Do I need to make an appointment?
    Yes, currently, I am the only esthetician and I only have one treatment room. While I want to see as many of you as possible, I usually get fully booked weeks in advance, so please make sure to make an appointment before coming in to see me. Thank you!
  • How many treatments can be provided at the same time?
    I'm the only esthetician at the salon, and we have a single treatment room, so it's not possible for me to provide multiple treatments at the same time. However, if you'd like to come in with a friend or partner for a spa day, I can offer back-to-back facials to accommodate both of you.
  • Is there a waiting room?
    I don't have a separate waiting room, but I have a table and chairs outside the treatment room where you can wait comfortably if you arrive early or if your friend or partner is receiving a treatment first.
  • What public transportation can I take to your salon?
    My salon is conveniently located near several public transportation options (Omotesando, Harajuku and Jingumae Stations) You can take the Tokyo Metro subway (Chiyoda, Ginza or Hanzomon Line), get off at Omotesando Station, and take the A1 exit, which is a 8min walk from the salon. You can also take the Tokyo Metro subway (Chiyoda or Fukutoshin Line), get off at Meiji-Jingumae Station, take the 6 or 7 Exit, which is a 5 min walk from the salon. Alternatively, you can take the JR train (Yamanote Line) to Harajuku Station, take the East Exit, which is a 12 min walk from the salon.
  • Where should I park?
    Although there is no parking available at the salon, there is a parking lot called Mitsuino Repark located just 1 minute walk from the salon. Parking lot address: Jingumae 5-16-6, Shibuya-Ku, Tokyo There is also parking space at Omotesando Hills, a popular shopping mall located just a 5 minute walk from the salon.
  • Which facial should I choose?
    I offer 60min, 90min and 120min customized facials. For the first facial at my salon, I typically recommend the 90min option to address all of your skin concerns, but the choice is ultimately up to you. Regardless of the facial you choose, each treatment is tailored to your unique skin type and concerns. The difference between each treatment can vary based on your skin, but in general, longer facials include additional modalities (such as LED light therapy, EMS microcurrent, Electroporation, Iontophoresis), as well as longer massages for extra relaxation and lifting. I am dedicated to providing personalized care and ensuring that you receive the best possible results from your facial treatment. If you have any questions or concerns, feel free to ask me at the time of booking. I am also happy to discuss your specific needs during your initial consultation.
  • What are included in your facial?
    All of my treatments are tailored to each client's unique skin type and concerns, so no two treatments are exactly the same. However, to give you an idea of what a typical treatment might include, here's a general outline: Cleansing Exfoliation Extraction Peel LED light therapy (to heal and stimulate collagen production) EMS microcurrent (for lifting and releasing muscle tension) Electroporation (to increase serum absorption) Relaxing and lifting massages Soothing Mask Gua sha stone massage Décolleté and Scalp massages Each of these steps is customized to meet the individual needs of the client, and the specific techniques and products used may vary from one treatment to the next.
  • How long do facial treatments take?
    I offer 60-minute, 90-minute, and 120-minute customized facials. These timeframes refer to the duration of the actual facial treatment itself. Please note that your visit takes longer than the facial length due to additional time needed for consultation and changing into the robe. Allow for approximately 15 minutes extra to account for these additional processes. You can arrive right at the appointment time.
  • Can I receive a facial if I am pregnant or breastfeeding?
    Yes, pregnant or breastfeeding women can safely receive a facial at my salon. If you are pregnant or breastfeeding, please let me know when booking your appointment so that I can ensure the proper care and safety.
  • Do you perform extraction?
    Extraction is an important part my facial treatments. While most skin can benefit from extraction, my goal is always to properly assess each client's skin and customize the treatment, so if extraction is not necessary or if you prefer to omit it, I will adjust the treatment to address other concerns to achieve the best results.
  • What is LED light therapy?
    LED red light therapy energizes skin cells, stimulates collagen production, while reducing inflammation and leaving your skin soft, plump and brighter. This technology was originally invented by NASA in the 1980s to grow plants on space shuttles. They later discovered that these lights offer healing properties to our skin as well. The LED panel I use has 1800 LEDs (deep red, 660nm wavelength) which provide anti-aging benefits. Many research studies show human cells respond best to red light in this specific wavelength.
  • What is EMS?
    In essence, EMS (Electric Muscle Stimulation) is a facial workout! It is a form of microcurrent therapy that uses low-level electrical currents to stimulate facial muscles. By targeting specific muscles in the face, EMS can help lift and firm the skin, reducing the appearance of wrinkles and sagging. In addition, EMS can help improve overall skin health by increasing blood circulation and lymphatic flow, as well as releasing muscle tension.
  • Do you ship internationally?
    Yes! I ship internationally and offer free international shipping for orders over 35,000 yen. (Please note that for domestic shipments within Japan, the minimum order value for free shipping is 9,900 yen.)
  • When can I expect my order?
    Orders placed within Japan typically arrive within 1-2 days. For international orders, delivery times may vary based on the destination, but currently, orders to the US and UK usually take 3-5 days. Once your order has been shipped, you'll receive a tracking number so you can stay updated on its location throughout the delivery process.
  • What is your return policy?
    If you're not entirely satisfied with your order, please contact me promptly at glowbytomoko@gmail.com to arrange a return. I am happy to offer a full refund for all goods returned within 14 days of purchase, given they remain in their original, unopened, and unused condition. Please note that shipping costs are non-refundable, and the customer is responsible for return shipping expenses. In the event that your purchase arrives damaged, kindly reach out to me within 24 hours of delivery with a photo of the damaged product in its shipping box. Your timely notification will enable me to provide you with the best possible assistance.
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